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OpenSky Uptake Intelligence

AI Powered Insight for Improving Therapy and Vaccination Adoption.

OpenSky Uptake Intelligence combines real-world data, AI, and expert consulting to help pharmaceutical and healthcare teams understand what drives or hinders adoption — and act on it.

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Uptake Intelligence: About the Service

Uptake Intelligence combines AI and human expertise to help pharmaceutical and healthcare organisations improve therapy and vaccine adoption.

Built on Microsoft Fabric, Azure AI, and Power BI, it turns complex data into actionable insight — connecting Market Access, Medical, and Commercial teams around measurable outcomes.

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Identify what drives or limits adoption.

Measure and optimize intervention impact.

Guide next-best actions using explainable AI.

How It Works

From Data to Decision...a continuous intelligence cycle.

 

 

The Uptake Intelligence Engine transforms complex real-world data into clear, actionable insight through a proven, six-step data-to-decision cycle.  The engine continually learns. Each new data refresh retrains the AI models, integrating fresh outcomes and feedback to enhance accuracy and insight relevance.

 

 

OpenSky Uptake Intelligence - How the Engine Works (4)

Uptake Intelligence Engine - The Process

Number 1

Ingest & Connect

Integrate internal and external sources (CRM, registry, claims, public health) securely in Microsoft Fabric.

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Analyze & Identify

AI uncovers behavioural, social, and clinical factors influencing adoption.

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Measure & Evaluate

Quantify the real-world impact of interventions and equity progress.

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Recommend & Optimize

AI agents propose targeted recommendations, validated by OpenSky consultants.

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Visualize & Collaborate

Power BI dashboards enable collaboration around shared insight.

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Learn & Evolve

Continuous learning and retraining ensure the model grows smarter over time.

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Proven Impact

60% year-on-year vaccination improvement

OpenSky Uptake Intelligence was used to analyse vaccination adoption for HPV in Slovakia, uncovering real-world drivers and barriers for MSD.
These insights guided targeted interventions that led to a 60% increase in vaccination coverage in just one year — demonstrating measurable impact through data-driven strategy.

First national vaccination uptake dashboard

Created, giving real-time visibility by region, gender, and provider type.

Insights guided targeted outreach

Improving awareness and equity across priority populations.

Joint project with MSD and the Ministry of Health Slovakia

Showcasing the power of cross-sector data collaboration.

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Built for Cross-Functional Pharmaceutical Teams

  • Market Access Teams; Quantify outcomes, ROI, and equity impact.
  • Medical Affair/RWE; Link clinical outcomes with real-world usage.
  • Commercial/Marketing; Identify which campaigns drive adoption.
  • Public Affairs/Policy; Use data to support stakeholder engagement.
  • Analytics/Data Science; Operationalise AI pipelines for ongoing insight.

OpenSky Uptake Intelligence transforms how these functions work together: giving each team access to the same evidence, insights, and performance metrics, while allowing them to interpret results through their own lens.
Market Access can measure value and equity, Medical can validate real-world evidence, Commercial can refine go-to-market activity, and Policy teams can demonstrate public-health impact — all powered by the same AI-driven insight engine.

By aligning strategy, evidence, and execution across departments, Uptake Intelligence helps pharma organisations move faster from data to decision — and from decision to measurable adoption outcomes.

Fast, Focused Results

From Data to Decision in Weeks

An engagement combines AI-driven analytics with human-led consulting to translate real-world data into clear, actionable insight.

Typical projects deliver measurable outcomes in 8–12 weeks, helping teams move quickly from discovery to visualised results — securely and at scale.

 

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ABOUT US

More of Our Pharma Data Work

DENMARK MAP

EU Flagship Dashboard Denmark

Denmark is a global leader in eHealth and electronic vaccination registries, with more than a decade of comprehensive HPV immunisation data managed by the Statens Serum Institut (SSI).
OpenSky’s VaxLens team transformed Denmark’s public vaccination data into a modern, interactive dashboard, providing a clearer, more accessible view of national HPV coverage trends.

 

Engage with the Denmark HPV Immunization Dashboard
OpenSky MSD Research Report Heatmap

HPV Electronic Registries Correlation Study

OpenSky was commissioned to analyse how Electronic Vaccination Registries (EVRs) influence Vaccine Coverage Rates (VCRs) across Europe and beyond.
Using HPV vaccination as a case study, the research produced a heatmap and scoreboard showing clear correlations between registry maturity and vaccination uptake.
The project has since expanded across the Asia–Pacific region through a collaboration between MSD, Microsoft, and Johnson & Johnson under the ECH Alliance’s Global Health Connector's Digital Health Society, providing unprecedented insight into EVR sophistication across 50+ countries.

Download the Report
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Advancing Vaccine Data Awareness in Switzerland

Switzerland faces unique challenges in vaccination monitoring, with fragmented systems across its 26 cantons and limited national coordination for Electronic Vaccination Registries (EVRs).
To support greater alignment among healthcare, policy, and public-health stakeholders, OpenSky conducted stakeholder consulting in Switzerland, sharing European insights and best practices to advance national strategies for vaccine monitoring and data-led public health improvement.

Listen to The MSD Slovakia Case Study - Join Our Webinar on Dec 11th

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Speakers:

Chair: Bleddyn Rees, Executive Chair, Global Health Connector

MSD Global Vaccines Team: Presenting MSD’s worldwide approach to strengthening vaccine uptake and confidence through digital and data-driven innovation, and introducing the Slovakia success story within a global strategy framework.

Ekaterina Ser, Global Vaccines Marketing, MSD: Case Study sharing how data-driven insight shaped the HPV vaccination campaign in Slovakia, and the measurable outcomes achieved.

William Flanagan, Director of Technology, OpenSky: Demonstrating how OpenSky's Uptake Intelligence, built on Azure AI, captures behavioural and data-driven signals to identify intervention opportunities and drive measurable vaccination outcomes.

Public Health Expert: A globally recognised thought leader in vaccine policy and public-health data.  (Stay tuned for the announcement of our public health expert next week)

ABOUT US

Why OpenSky

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Experience

Over 20 years delivering complex data transformation projects across healthcare, pharma, and public-sector systems — including long-term partnerships with MSD and other industry leaders.

 

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Technology

Built on Microsoft Fabric and Azure AI, providing a scalable, secure, and compliant architecture for healthcare analytics and cross-functional collaboration.

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Impact

Proven results from national-scale projects such as vaccination uptake analytics, public health data reporting, and AI-powered adoption intelligence, improving access, equity, and patient outcomes.

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Insight

Expertise in transforming clinical, epidemiological, and behavioural data into actionable intelligence for Market Access, Medical, and Policy teams — supported by our in-house R&D department and collaborations with leading research and innovation centres including: CeADAR (Ireland’s National Centre for Applied AI), The Alan Turing Institute and the Global Health Connector Partnership.