OpenSky Uptake Intelligence
AI Powered Insight for Improving Therapy and Vaccination Adoption.
OpenSky Uptake Intelligence combines real-world data, AI, and expert consulting to help pharmaceutical and healthcare teams understand what drives or hinders adoption — and act on it.
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Uptake Intelligence: About the Service
Uptake Intelligence combines AI and human expertise to help pharmaceutical and healthcare organisations improve therapy and vaccine adoption.
Built on Microsoft Fabric, Azure AI, and Power BI, it turns complex data into actionable insight — connecting Market Access, Medical, and Commercial teams around measurable outcomes.
Identify what drives or limits adoption.
Measure and optimize intervention impact.
Guide next-best actions using explainable AI.
How It Works
From Data to Decision...a continuous intelligence cycle.
The Uptake Intelligence Engine transforms complex real-world data into clear, actionable insight through a proven, six-step data-to-decision cycle. The engine continually learns. Each new data refresh retrains the AI models, integrating fresh outcomes and feedback to enhance accuracy and insight relevance.
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Uptake Intelligence Engine - The Process
Ingest & Connect
Integrate internal and external sources (CRM, registry, claims, public health) securely in Microsoft Fabric.
Analyze & Identify
AI uncovers behavioural, social, and clinical factors influencing adoption.
Measure & Evaluate
Quantify the real-world impact of interventions and equity progress.
Recommend & Optimize
AI agents propose targeted recommendations, validated by OpenSky consultants.
Visualize & Collaborate
Power BI dashboards enable collaboration around shared insight.
Learn & Evolve
Continuous learning and retraining ensure the model grows smarter over time.
Proven Impact
60% year-on-year vaccination improvement
In Slovakia, OpenSky Uptake Intelligence was used to analyse HPV vaccination adoption, uncovering real-world drivers and barriers.
These insights guided targeted interventions that led to a 60% increase in vaccination coverage in just one year — demonstrating measurable impact through data-driven strategy.
First national HPV uptake dashboard
Created, giving real-time visibility by region, gender, and provider type.
Insights guided targeted outreach
Improving awareness and equity across priority populations.
Joint project with MSD Slovakia and the Ministry of Health
Showcasing the power of cross-sector data collaboration.

Built for Cross-Functional Pharmaceutical Teams
- Market Access Teams; Quantify outcomes, ROI, and equity impact.
- Medical Affair/RWE; Link clinical outcomes with real-world usage.
- Commercial/Marketing; Identify which campaigns drive adoption.
- Public Affairs/Policy; Use data to support stakeholder engagement.
- Analytics/Data Science; Operationalise AI pipelines for ongoing insight.
OpenSky Uptake Intelligence transforms how these functions work together: giving each team access to the same evidence, insights, and performance metrics, while allowing them to interpret results through their own lens.
Market Access can measure value and equity, Medical can validate real-world evidence, Commercial can refine go-to-market activity, and Policy teams can demonstrate public-health impact — all powered by the same AI-driven insight engine.
By aligning strategy, evidence, and execution across departments, Uptake Intelligence helps pharma organisations move faster from data to decision — and from decision to measurable adoption outcomes.
ABOUT US
Why OpenSky
Experience
Over 20 years delivering complex data transformation projects across healthcare, pharma, and public-sector systems — including long-term partnerships with MSD and other industry leaders.
Technology
Built on Microsoft Fabric and Azure AI, providing a scalable, secure, and compliant architecture for healthcare analytics and cross-functional collaboration.
Impact
Proven results from national-scale projects such as vaccination uptake analytics, public health data reporting, and AI-powered adoption intelligence, improving access, equity, and patient outcomes.
Insight
Expertise in transforming clinical, epidemiological, and behavioural data into actionable intelligence for Market Access, Medical, and Policy teams — supported by our in-house R&D department and collaborations with leading research and innovation centres including: CeADAR (Ireland’s National Centre for Applied AI), The Alan Turing Institute and the Global Health Connector Partnership.
Fast, Focused Results
From Data to Decision in Weeks
An engagement combines AI-driven analytics with human-led consulting to translate real-world data into clear, actionable insight.
Typical projects deliver measurable outcomes in 8–12 weeks, helping teams move quickly from discovery to visualised results — securely and at scale.

